Green Tea (providing polyphenols and caffeine):
Green tea has been utilized as a Botanical Ingredient in traditional medicine for centuries. The bulk of the science shows polyphenols give green tea its unique and special power. For years, scientists have recognized that polyphenols in green tea exhibit a powerful ability to protect brain cells from free radical activity.*
Researchers have stated:
“Green tea catechin polyphenols, formally thought to be a simple radical scavenger, are now considered to invoke a spectrum of cellular mechanisms of action related to their neuroprotective activity. These include pharmacological activities like iron chelation, scavenging of radicals, activation of survival genes and cell signaling pathways, and regulation of mitochondrial function and possibly of the ubiquitin-proteasome system.* As a consequence these compounds are receiving significant attention as cytoprotective agents.”*7
In addition, Green tea provides naturally occurring caffeine. In a definitive report (Caffeine for the Sustainment of Mental Task Performance. Formulations for Military Operations), the Institute of Medicine Food and Nutrition Board Committee on Military Nutrition Research concluded that the consumption of caffeine enhances both cognitive functioning capabilities and neuromuscular coordination and that these effects can persist for hours post-consumption.*8
7: Mandel S, Youdim MB. Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radic Biol Med. 2004 Aug 1;37 (3):304-17.
8: Institute of Medicine Food and Nutrition Board Committee on Military Nutrition Research. Doses and delivery mechanisms. In: Institute of Medicine Food and Nutrition Board Committee on Military Nutrition Research. Caffeine for the Sustainment of Mental Task Performance. Formulations for Military Operations. National Academy Press, Washington, DC, 2001, pp. 61-65.